アスチルビン
アスチルビン(Astilbin)は、フラバノノールの一つである。アスチルビンは(2R-trans)型異性体、ネオイソアスチルビンは(2S-cis)型異性体、イソアスチルビンは(2R-cis)型異性体である[2]。
アスチルビン | |
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(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one | |
別称 Isoastilbin Neoastilbin Neoisoastilbin Taxifolin 3-O-rhamnoside Taxifolin 3-rhamnoside (2R-trans)-3-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-2-(3,4- dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one[1] | |
識別情報 | |
CAS登録番号 | 54141-72-9 |
PubChem | 119258 |
ChemSpider | 106533 |
KEGG | C17449 |
ChEBI | |
ChEMBL | CHEMBL486017 |
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特性 | |
化学式 | C21H22O11 |
モル質量 | 450.39 g/mol |
外観 | 茶色粉末[1] |
特記なき場合、データは常温 (25 °C)・常圧 (100 kPa) におけるものである。 |
天然の存在
アスチルビンは、セイヨウオトギリ、Dimorphandra mollis[3]、Harungana madagascariensisの葉[4]、Astilbe thunbergiiの根茎、Astilbe odontophyllaの根[5]、ドブクリョウの根茎[6]、Hymenaea martianaの樹皮[7] で見られる。
利用
ヤガ科のAnticarsia gemmatalisとSpodoptera frugiperdaに対する殺虫剤として作用する[3]。また、in vitroでの抗菌活性[4]及び火傷治癒の活性[5]を示す。中国医学で用いられる[6]。
出典
- http://anwabio.com/asti.htm%5B%5D
- Astilbin on PubChem
- Biological activity of astilbin from Dimorphandra mollis against Anticarsia gemmatalis and Spodoptera frugiperda, Luciane G Batista Pereira, Fernando Petacci, Joao B Fernandes, Arlene G Correa, Paulo C Vieira 1, M Fatima G F da Silva, Osmar Malaspina, 2002
- Isolation and in vitro antibacterial activity of astilbin, the bioactive flavanone from the leaves of Harungana madagascariensis Lam. ex Poir. (Hypericaceae), B. Moulari, Y. Pellequer, H. Lboutounne, C. Girard, J.-P. Chaumont, J. Millet and F. Muyard,
- Effects of Astilbe thunbergii rhizomes on wound healing: Part 1. Isolation of promotional effectors from Astilbe thunbergii rhizomes on burn wound healing, Yoshiyuki Kimura, Maho Sumiyoshi and Masahiro Sakanaka, 2006
- First synthesis of astilbin, biologically active glycosyl flavonoid isolated from Chinese folk medicine, Ken Ohmori, Hiroki Ohrui and Keisuke Suzuki, 2000
- Isolation, Chemical Identification and Pharmacological Evaluation of Eucryphin, Astilbin and Engelitin Obtained from the Bark of Hymenaea martiana. Eliane Carneiro, Joao B. Calixto, Franco Delle Monacheand Rosendo A. Yunes, Pharmaceutical Biology, 1993, Vol. 31, No. 1, Pages 38-46
- Levels of Stilbene Oligomers and Astilbin in French Varietal Wines and in Grapes during Noble Rot Development, Nicolas Landrault, Fabienne Larronde, Jean-Claude Delaunay, Chantal Castagnino, Joseph Vercauteren, Jean-Michel Merillon, Francis Gasc, Gerard Cros and Pierre-Louis Teissedre, J. Agric. Food Chem., 2002, 50 (7), pages 2046-2052, doi:10.1021/jf010794g
- Identification of a New Metabolite of Astilbin, 3'-O-Methylastilbin, and Its Immunosuppressive Activity against Contact Dermatitis, Jianming Guo, Feng Qian, Jianxin Li, Qiang Xu, Ting Chen, 2006
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